The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma.
Mardonny Bruno de Oliveira ChagasValécia de Cássia Mendonça da CostaClaudio MontenegroMaria do Carmo Alves de LimaMichelle Melgarejo da RosaMichelly Cristiny PereiraMoacyr Jesus Barreto de Melo RêgoMaira Galdino da Rocha PittaPublished in: Current cancer drug targets (2024)
Finally, topoisomerase II was inhibited. These results indicate the potential ap-plication of LPSF/AC05 in cancer therapy.