Withania frutescens. L Extract: Phytochemical Characterization and Acute and Repeated Dose 28-Day Oral Toxicity Studies in Mice.

Abdelfattah E L Moussaoui Mohammed Bourhia Fatima Zahra JawhariImane Es-SafiSyed Saeed AliAhmed BariHafiz Majid MahmoodDalila BoustaAmina Bari

Published in: BioMed research international (2020)

The outcome of this work showed no toxic effect of W. frutescens in mice up to dose 2000 mg/kg bodyweight. Therefore, this study could scientifically validate further traditional use with safety in the range of tested doses.

Keyphrases

high fat diet induced
oxidative stress
liver failure
type diabetes
wild type
insulin resistance
drug induced
case control
aortic dissection
anti inflammatory
acute respiratory distress syndrome