HIP1R acts as a tumor suppressor in gastric cancer by promoting cancer cell apoptosis and inhibiting migration and invasion through modulating Akt.

Jinliang ZhuXin WangHuiyuan GuanQiong XiaoZhonghua WuJinxin ShiFei ZhangPeng GaoYongxi Song Zhen-Ning Wang

Published in: Journal of clinical laboratory analysis (2020)

Our data indicate that HIP1R may act as a potential diagnostic biomarker and a tumor suppressor gene in GC, potentially representing a novel therapeutic target for future GC treatment.

Keyphrases

signaling pathway
cell proliferation
total hip arthroplasty
papillary thyroid
gas chromatography
genome wide
squamous cell
copy number
big data
current status
combination therapy
risk assessment
young adults
high resolution
data analysis
tandem mass spectrometry