Non-Steroidal Anti-Inflammatory Drugs and Risk of Acute Kidney Injury and Hyperkalemia in Older Adults: A Retrospective Cohort Study and External Validation of a Clinical Risk Model.

Cynthia Ciwei LimNgiap Chuan TanEdmund Pek Siang TeoHanis Bte Abdul KadirJia Liang KwekYong Mong BeeAndrew Teck Wee AngSu Hooi TeoManish KaushikChieh Suai TanJason Chon Jun Choo

Published in: Drugs & aging (2021)

Longer NSAID duration and systemic compared with topical route were associated with incremental odds for acute renal events. Further studies are required to improve the available risk model to guide NSAID prescriptions in older adults.

Keyphrases

anti inflammatory drugs
acute kidney injury
physical activity
liver failure
cardiac surgery
drug induced
hepatitis b virus