Morroniside ameliorates glucocorticoid-induced osteoporosis and promotes osteoblastogenesis by interacting with sodium-glucose cotransporter 2.

Hou-Zhi YangRunbei DongYutao JiaYuqiao LiGan LuoTianhao LiYao LongShuang LiangShanshan LiXin JinTianwei Sun

Published in: Pharmaceutical biology (2023)

These findings demonstrated that MOR treatment promoted osteoblastogenesis and ameliorated glucocorticoid-induced OP by targeting SGLT2, which may provide therapeutic potential in managing glucocorticoid-induced OP.

Keyphrases

diabetic rats
drug induced
oxidative stress
postmenopausal women
endothelial cells