Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization.
E OlivaDavid MathironE BertautD LandyD CailleuSerge PilardC ClémentEric CourotVéronique BonnetFlorence Djedaini-PilardPublished in: RSC advances (2018)
trans -Resveratrol (RSV) is a natural phenolic molecule of the stilbene family known for its anti-oxidant properties in the field of nutraceuticals and cosmetics. Its production by grapevine cell suspensions is induced by the addition to the culture medium of elicitor compounds, methyl jasmonate (MeJA) and cyclodextrins (CDs). Physico-chemical studies were performed to understand the mechanism of action of CDs on this bioproduction of RSV. Inclusion complexes of RSV in CDs were first observed and then interactions with MeJA were identified using various analytical techniques such as UV and nuclear magnetic resonance (NMR) spectroscopies, mass spectrometry (MS) and isothermal titration calorimetry (ITC).
Keyphrases
- quantum dots
- magnetic resonance
- mass spectrometry
- respiratory syncytial virus
- capillary electrophoresis
- respiratory tract
- liquid chromatography
- high resolution
- case control
- visible light
- single cell
- multiple sclerosis
- cell therapy
- ms ms
- gas chromatography
- ionic liquid
- contrast enhanced
- mesenchymal stem cells
- bone marrow
- tandem mass spectrometry
- anti inflammatory
- computed tomography
- solid state