TREC/KREC Levels and T and B Lymphocyte Subpopulations in COVID-19 Patients at Different Stages of the Disease.

Andrei Anatolyevich SavchenkoElena TikhonovaIgor KudryavtsevDmitry Anatolievich Kudlay Ilya Korsunsky Vasily Dmitrievich Belenyuk Alexandr Gennadyevich Borisov

Published in: Viruses (2022)

The assessment of correlations between TREC and T cell subsets as well as KREC levels and B cell subset counts in patients with acute COVID-19 and COVID-19 survivors has shown that blood concentrations of TREC and KREC are sensitive indicators of the stage of antigen-independent differentiation of adaptive immunity cells. The results of the TREC and KREC analysis correlated with the stages of COVID-19 and differed depending on the outcome of COVID-19.

Keyphrases

coronavirus disease
sars cov
respiratory syndrome coronavirus
peripheral blood
induced apoptosis
signaling pathway
oxidative stress