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Single-cell Transcriptomic Analysis of Oral Masticatory and Lining Mucosa-derived Mesenchymal Stromal Cells.

Ilan PinkhasovLiron KabakovCarlos E NemcovskyMiron WeinrebPnina SchlesingerOmer BenderMaayan GalDaniel Z BarEvegeny Weinberg
Published in: Journal of clinical periodontology (2023)
Our previous work demonstrated that cells from the lining and masticatory oral mucosae are phenotypically heterogeneous. Here, we extend these findings to show that these changes are not the results of differences in averages, but rather represent two distinct cell populations with mesenchymal stem cells more common in masticatory mucosa. These features may contribute to specific physiological functions and have relevance for potential therapeutic interventions. This article is protected by copyright. All rights reserved.
Keyphrases
  • single cell
  • mesenchymal stem cells
  • rna seq
  • bone marrow
  • cell therapy
  • high throughput
  • physical activity
  • umbilical cord
  • stem cells