Necrotic lymphoma in a patient with post-transplantation lymphoproliferative disorder: ultrasonography and CT findings with pathologic correlation.
Minsu LeeSang-Kyum KimEun Yong ChungJin-Young ChoiChang Moo KangJoon Seok LimMyeong Jin KimHon Soul KimPublished in: Ultrasonography (Seoul, Korea) (2014)
Seventeen months after kidney transplantation for the treatment of nephrotic syndrome, a retroperitoneal mass was incidentally detected in a 30-year-old man during routine follow-up. Ultrasonography revealed a mass measuring 5.5 cm×4.3 cm located between the liver and the atrophic right kidney, which showed markedly heterogeneous internal echogenicity. Contrast-enhanced computed tomography displayed a mild degree of enhancement only at the periphery of the mass, while the center lacked perceivable intensification. The patient underwent surgical resection. The final pathological diagnosis was non-Hodgkin lymphoma (diffuse large B-cell lymphoma), and extensive necrosis was observed on microscopic examination. We found that the prominent heterogeneous echogenicity of the mass (an unusual finding of lymphoma) demonstrated on ultrasonography is a result of extensive necrosis, which may sometimes occur in patients with post-transplantation lymphoproliferative disorder.
Keyphrases
- contrast enhanced
- diffuse large b cell lymphoma
- epstein barr virus
- computed tomography
- magnetic resonance imaging
- diffusion weighted
- magnetic resonance
- diffusion weighted imaging
- dual energy
- positron emission tomography
- case report
- stem cells
- radiation therapy
- single cell
- cell therapy
- smoking cessation
- rectal cancer
- minimally invasive
- locally advanced