Abnormal functional connectivity in the right dorsal anterior insula associated with cognitive dysfunction in patients with type 2 diabetes mellitus.

Man Wang Dongsheng ZhangJie GaoFei QiYu SuYumeng LeiZhirong ShaoKai AiMin TangXiaoling Zhang

Published in: Brain and behavior (2022)

Patients with T2DM exhibit abnormal FC between the right dAI and the CEN and DMN. This may be one of the neuromechanisms of cognitive impairment in patients with T2DM. In addition, reduced FC between the right dAI and the right inferior frontal gyrus may be related to abnormal attention regulation in patients with T2DM.

Keyphrases

functional connectivity
resting state
cognitive impairment
glycemic control
working memory
spinal cord
neuropathic pain
metabolic syndrome
skeletal muscle
adipose tissue