Inflammation biomarkers in the intracranial blood are associated with outcome in patients with ischemic stroke.
Cyril DargazanliMarine BlaquièreMarinette MoynierFrédéric de BockJulien LabreucheAdrien Ter SchiphorstImad DerrazRăzvan Alexandru RaduGregory GascouPierre Henri LefevreFrancesca RapidoJulien FendeleurCaroline ArquizanRomain BourcierPhilippe MarinPaolo MachiFederico CagnazzoChristophe HirtzVincent CostalatNicola MarchiPublished in: Journal of neurointerventional surgery (2024)
Our findings show a signature of blood inflammatory factors at the cerebrovascular occlusion site. The correlations between these acute-stage biomarkers and mRS score outcome support an avenue for add-on and localized immune modulatory strategies in AIS.