Urine metabolomics reveals biomarkers and the underlying pathogenesis of diabetic kidney disease.

Maolin LuoZeyu ZhangYongping LuWeifeng FengHongwei WuLijing FanBaozhang GuanYong DaiDonge TangXiangnan DongChen YunBerthold HocherHaiping LiuQiang LiLianghong Yin

Published in: International urology and nephrology (2022)

This work reveals the metabolic alterations in T2DM and DKD, constructs a combined model to distinguish them and delivers a novel strategy for studying the underlying mechanism and treatment of DKD.

Keyphrases

type diabetes
mass spectrometry
adipose tissue
combination therapy
metabolic syndrome
glycemic control
replacement therapy