Safety and efficacy of intravesical chemotherapy and hyperthermia in the bladder: results of a porcine study.
Wei Phin TanAndrew ChangSteven C BrousellDominic C GrimbergJoseph J FantonyThomas A LongoWiguins EtienneIvan SpasojevicPaolo MaccariniBrant A InmanPublished in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2021)
Convective bladder hyperthermia using the Combat BRS device is safe and the temperature can be maintained at 43 °C. Hyperthermia therapy may increase MMC penetration into the bladder wall but does not result in an increase of MMC levels in other organs.