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CAT25 defines microsatellite instability in colorectal cancer by high-resolution melting PCR.

A G SánchezI JuanedaH EynardA L BasquieraE PalazzoP CalafatV PallaPablo Alberto RomagnoliT Alvarellos
Published in: British journal of biomedical science (2020)
We developed and validated a new HRM-PCR assay to detect CAT25 instability. Our findings showed a limited allelic size variation of CAT25 and highlighted to CAT25 as a promising marker for MSI analysis.
Keyphrases
  • high resolution
  • mass spectrometry
  • liquid chromatography
  • genetic diversity