Differences in vaginal microbiota, host transcriptome and proteins in women with bacterial vaginosis are associated with metronidazole treatment response.
Joyce Serebrenik SultanTao WangRichard HunteSujatha SrinivasanJessica McWaltersGregory K TharpSteven E BosingerTina L FiedlerJessica M AtrioKerry MurphyRebecca BarnettLaurie R RayMeighan L KrowsDavid N FredricksElizabeth IrunguKenneth NgureNelly MugoJeanne MarrazzoMarla J KellerBetsy C HeroldPublished in: The Journal of infectious diseases (2021)
Response to metronidazole is characterized by significant changes in chemokines and related transcripts suggesting that treatments that promote these pathways may prove beneficial.