Absolute stereochemical determination of 1,2-diols via complexation with dinaphthyl borinic acid.
Saeedeh Torabi KohlbouniAritra SarkarJun ZhangXiaoyong LiBabak BorhanPublished in: Chirality (2020)
Rapid derivatization of chiral 1,2-diols with dinaphthyl borinic acid (DBA) leads to a cyclic boronate, enabling the absolute stereochemical prediction via exciton-coupled circular dichroic (ECCD) of the naphthyl groups. Aryl- and alkyl-substituted 1,2-diols derivatized with DBA yield a predictable ECCD, which is also in agreement with theoretical predictions derived from computationally minimized structures.
Keyphrases
- ionic liquid
- solid phase extraction
- ms ms
- high resolution
- liquid chromatography tandem mass spectrometry
- simultaneous determination
- high performance liquid chromatography
- gas chromatography mass spectrometry
- loop mediated isothermal amplification
- sensitive detection
- molecular dynamics simulations
- quantum dots
- visible light
- energy transfer