Resistance to endocrine therapy in breast cancer: molecular mechanisms and future goals.

Małgorzata SzostakowskaAlicja Trębińska-StryjewskaEwa Anna GrzybowskaAnna Fabisiewicz

Published in: Breast cancer research and treatment (2018)

This comprehensive review summarizes molecular mechanisms associated with resistance to anti-estrogen therapy, focusing on genetic alterations, stress responses, cell survival mechanisms, and cell reprogramming.

Keyphrases

cell therapy
single cell
stem cells
genome wide
current status
public health
copy number
dna methylation
replacement therapy
breast cancer risk