Immune cell topography of head and neck cancer.
Tara MuijlwijkDennis N L M NijenhuisSonja H GanzevlesFatima EkhlasCarmen Ballesteros-MerinoLaura A N PeferoenElisabeth BloemenaBernard A FoxJos B PoellC René LeemansRuud H BrakenhoffRieneke van de VenPublished in: Journal for immunotherapy of cancer (2024)
We comprehensively described the TIME of HNSCC using a unique data set of resection specimens. We discovered that the composition, as well as the relative localization of immune cells in the TIME, differed in distinct anatomical sites of the head and neck.