Pharmacogenetics of ABCB1, CDA, DCK, GSTT1, GSTM1 and outcomes in a cohort of pediatric acute myeloid leukemia patients from Colombia.

Luz Karime YunisAdriana Linares-BallesterosNelson AponteGisela BarrosJohnny GarcíaLaura NiñoGloria UribeEdna QuinteroJuan J Yunis

Published in: Cancer reports (Hoboken, N.J.) (2022)

Our results highlight the importance of pharmacogenetic analysis in pediatric AML, particularly in populations with a high degree of admixture, and might be useful as a future tool for patient stratification for treatment.

Keyphrases

acute myeloid leukemia
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
allogeneic hematopoietic stem cell transplantation
peritoneal dialysis
prognostic factors
type diabetes
current status
patient reported outcomes
skeletal muscle
insulin resistance
weight loss
smoking cessation