Dual glucagon-like peptide-1 and glucagon receptor agonism reduces energy intake in type 2 diabetes with obesity.
Rajna GolubicJane KennetVictoria E R ParkerDarren RobertsonDan LuoLars HansenLutz JermutusPhilip AmberyMaria RyaboshapkinaManasa SurakalaRhianna C LakerMichelle VenablesAlbert KoulmanAdrian ParkMark L EvansPublished in: Diabetes, obesity & metabolism (2024)
Weight loss with cotadutide is primarily driven by reduced EI, with relatively small compensatory changes in EE.