Inhibition of HYBID (KIAA1199)-mediated hyaluronan degradation and anti-wrinkle effect of Geranium thunbergii extract.

Hiroyuki YoshidaKohei YamazakiAya KomiyaMika AokiTomomi NakamuraShinya KasamatsuTakeshi MurataTetsuya SayoYasunori OkadaYoshito Takahashi

Published in: Journal of cosmetic dermatology (2018)

Geranium thunbergii extract inhibited HYBID-mediated HA degradation in vitro and showed anti-wrinkle activity in vivo accompanying the improvement in skin elasticity. Our study provides a possible strategy for anti-wrinkle care through inhibition of HYBID-mediated HA degradation.

Keyphrases

healthcare
oxidative stress
anti inflammatory