Identification and utilization of copy number information for correcting Hi-C contact map of cancer cell lines.
Ahmed Ibrahim Samir KhalilSiti Rawaidah Binte Mohammad MuzakiAnupam ChattopadhyayAmartya SanyalPublished in: BMC bioinformatics (2020)
HiCNAtra is a Hi-C-based computational tool that provides an analytical and visualization framework for DNA copy number profiling and chromatin contact map correction of karyotypically abnormal cell lines. HiCNAtra is an open-source software implemented in MATLAB and is available at https://github.com/AISKhalil/HiCNAtra .
Keyphrases
- copy number
- mitochondrial dna
- genome wide
- papillary thyroid
- dna methylation
- gene expression
- high density
- circulating tumor
- squamous cell
- dna damage
- transcription factor
- single cell
- single molecule
- health information
- healthcare
- lymph node metastasis
- childhood cancer
- data analysis
- bioinformatics analysis
- young adults
- social media
- nucleic acid