Virus-positive Merkel Cell Carcinoma Is an Independent Prognostic Group with Distinct Predictive Biomarkers.

Kelly L HarmsLili ZhaoBryan JohnsonXiao-Ming WangShannon CarskadonNallasivam PalanisamyDaniel R RhodesRahul MannanJosh N VoJae Eun ChoiMay P ChanDouglas R FullenRajiv M PatelJaved SiddiquiVincent T MaSteven HrycajScott A McLeanTasha M HughesChristopher K BichakjianScott A Tomlins

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

MCPyV status is an independent prognostic factor for MCC. Features of the tumor genome, transcriptome, and microenvironment may modify prognosis in a manner specific to viral status. MCPyV status has clinicopathologic significance and allows for identification of additional prognostic subgroups.

Keyphrases

prognostic factors
stem cells
genome wide
sars cov
rna seq
bioinformatics analysis