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Validation of Conversion Factors for Therapeutic Drug Monitoring of Lacosamide, Lamotrigine, and Levetiracetam in Dried Capillary Blood.

Anne HagemannDennis KlimpelElisabeth SchmitterChristian G BienBertin DufauxTheodor W MayChristian Brandt
Published in: Therapeutic drug monitoring (2022)
Estimating serum concentrations using capillary blood concentrations is feasible and accurate for LCM and LEV over a wide concentration range, as found in clinical practice. The applicability of this method for LTG is limited by its greater variability at higher concentrations; however, acceptable results were achieved for the large proportion of patients with low and medium LTG concentrations.
Keyphrases
  • clinical practice
  • high resolution