Enhanced SLC35B2/SAV1 sulfation axis promotes tumor growth by inhibiting Hippo signaling in HCC.

Bo He Zhao HuangSiyuan QinPeilan PengXirui DuanLongqin WangQin YeKui WangJingwen JiangBowen LiRui Liu Canhua Huang

Published in: Hepatology (Baltimore, Md.) (2024)

Our findings reveal a regulatory mechanism of the SLC35B2/SAV1 sulfation axis in response to oxidative stress, highlighting its potential as a promising therapeutic target for HCC.

Keyphrases

oxidative stress
signaling pathway
transcription factor
genome wide
dna damage
single cell
ischemia reperfusion injury
induced apoptosis
gene expression
diabetic rats
dna methylation