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Phthalate and phthalate replacement concentrations in relationship to adiposity in a multi-racial cohort of children.

Kelly J HuntPamela L FergusonMichael S BloomBrian NeelonJohn PearceSarah CommodoreRoger B NewmanJames R RobertsLisa BainWilliam BaldwinWilliam A GrobmanAnthony C SciscioneAlan T TitaMichael P NageotteKristy PalomaresDaniel W SkupskiCuilin ZhangRonald WapnerJohn E Vena
Published in: International journal of obesity (2005) (2024)
We report an inverse association between child urinary DINCH levels, a non-phthalate plasticizer that has replaced DEHP in several applications, and BMI z-score, waist circumference z-score and % body fat in children. Few prior studies of phthalates and their replacements in children have been conducted in diverse populations. Moreover, DINCH has not received a great deal of attention or regulation, but it is a common exposure. In summary, understanding the ubiquitous nature of these chemical exposures and ultimately their sources will contribute to our understanding of their relationship with obesity.
Keyphrases
  • body mass index
  • young adults
  • insulin resistance
  • weight gain
  • type diabetes
  • metabolic syndrome
  • mental health
  • drinking water
  • adipose tissue
  • physical activity
  • genetic diversity