Phthalate and phthalate replacement concentrations in relationship to adiposity in a multi-racial cohort of children.
Kelly J HuntPamela L FergusonMichael S BloomBrian NeelonJohn PearceSarah CommodoreRoger B NewmanJames R RobertsLisa BainWilliam BaldwinWilliam A GrobmanAnthony C SciscioneAlan T TitaMichael P NageotteKristy PalomaresDaniel W SkupskiCuilin ZhangRonald WapnerJohn E VenaPublished in: International journal of obesity (2005) (2024)
We report an inverse association between child urinary DINCH levels, a non-phthalate plasticizer that has replaced DEHP in several applications, and BMI z-score, waist circumference z-score and % body fat in children. Few prior studies of phthalates and their replacements in children have been conducted in diverse populations. Moreover, DINCH has not received a great deal of attention or regulation, but it is a common exposure. In summary, understanding the ubiquitous nature of these chemical exposures and ultimately their sources will contribute to our understanding of their relationship with obesity.