Profiling of antioxidant properties and identification of potential analgesic inhibitory activities of Allophylus villosus and Mycetia sinensis employing in vivo, in vitro, and computational techniques.

Md Nur Kabidul AzamPartha BiswasAmia KhandkerMd Mohaimenul Islam TareqSadia Jannat TauhidaTushar Ahmed ShishirShabana BibiMd Asraful AlamMd Nazmul Hasan ZilaniNorah A AlbekairiAbdulrahman AlshammariMohammad Shahedur RahmanMd Nazmul Hasan

Published in: Journal of ethnopharmacology (2024)

Phytocompounds from A. villosus & M. sinensis exhibited potential antagonist activity against human 15-lipoxygenase-2 and cyclooxygenase-2 proteins. The effective ester compounds from these plants performed more potential anti-nociceptive activity which could be used as a drug in future.

Keyphrases

endothelial cells
human health
neuropathic pain
oxidative stress
risk assessment
current status
climate change
spinal cord