Xinfeng Capsule Inhibits Pyroptosis and Ameliorates Myocardial Injury in Rats with Adjuvant Arthritis via the GAS5/miR-21/TLR4 Axis.

Wanlan FuYunxiang CaoJian LiuChuanbing HuangKaiyan ShuNanfei Zhu

Published in: Drug design, development and therapy (2024)

XFC alleviated myocardial injury in AA rats by regulating the GAS5/miR-21/TLR4 axis and inhibiting pyroptosis and pro-inflammatory cytokine secretion.

Keyphrases

cell proliferation
long non coding rna
toll like receptor
inflammatory response
long noncoding rna
nlrp inflammasome
immune response
room temperature
early stage
rheumatoid arthritis
left ventricular
nuclear factor
signaling pathway
carbon dioxide
heart failure