Hyaluronic acid plasma levels during high versus low tidal volume ventilation in a porcine sepsis model.

Rainer ThomasTanghua LiuArno SchadRobert RuemmlerJens KamufRené RisselThomas OttMatthias DavidErik K HartmannAlexander Ziebart

Published in: PeerJ (2022)

In a porcine model of septic shock and ARDS, the serum hyaluronic acid levels were significantly elevated in both sepsis groups in comparison to the no-LPS-group. Intergroup comparison between lung protective ventilated and high tidal ventilated animals revealed no significant differences in the serum hyaluronic acid levels.

Keyphrases

hyaluronic acid
septic shock
acute respiratory distress syndrome
intensive care unit
mechanical ventilation
carbon dioxide
extracorporeal membrane oxygenation
acute kidney injury
respiratory failure