Autoantigens in the trabecular meshwork and glaucoma-specific alterations in the natural autoantibody repertoire.

Vanessa M BeutgenCarsten SchmelterNorbert PfeifferFranz H Grus

Published in: Clinical & translational immunology (2020)

This study provides new insights into autoimmunity in health and glaucoma. Bioinformatic analysis of POAG-related autoantigens showed a strong association with the PDGFRB pathway and also increased levels of PNMA2, TARS, and C1QBP autoantibodies in the serum of POAG patients as potential glaucoma biomarkers.

Keyphrases

end stage renal disease
optic nerve
ejection fraction
healthcare
chronic kidney disease
newly diagnosed
mental health
prognostic factors
systemic lupus erythematosus
peritoneal dialysis
human health
body composition
climate change
social media
postmenopausal women
patient reported
drug induced
bone loss