Midgestation Leptin Infusion Induces Characteristics of Clinical Preeclampsia in Mice, Which Is Ablated by Endothelial Mineralocorticoid Receptor Deletion.

Jessica L FaulknerDerrian WrightGalina AntonovaIris Z JaffeSimone KennardEric J Belin de Chantemèle

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

Collectively, these data indicate that leptin infusion in midgestation induces endothelial dysfunction, hypertension, and fetal growth restriction in pregnant mice, which is ablated by ECMR deletion.

Keyphrases

high fat diet induced
low dose
blood pressure
endothelial cells
pregnant women
electronic health record
big data
metabolic syndrome
binding protein
artificial intelligence