In vitro efficacy of pro- and anticoagulant strategies in compensated and acutely ill patients with cirrhosis.

J P LuyendykSimone KleissVishal C PatelCaleb FisherJelle AdelmeijerSarah BosArjuna SinganayagamSidsel H StoyDebbie L ShawcrossWilliam Bernal

Published in: Liver international : official journal of the International Association for the Study of the Liver (2018)

These in vitro data suggest little prohaemostatic effect of fresh frozen plasma and recombinant factor VIIa in acutely ill cirrhotics, whereas prothrombin complex concentrate and fibrinogen concentrate clearly improved haemostasis. Furthermore, our data suggest the requirement for dose adjustments of commonly used anticoagulants in these patients.

Keyphrases

end stage renal disease
electronic health record
ejection fraction
newly diagnosed
chronic kidney disease
big data
venous thromboembolism
peritoneal dialysis
prognostic factors
patient reported outcomes
data analysis