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Co-exposure to multiple air pollutants, genetic susceptibility, and the risk of myocardial infarction onset: A cohort analysis of the UK Biobank participants.

Zhou JiangShuo ZhangTongyu GaoKeying ChenYuxin LiuYing LiuTing WangPing Zeng
Published in: European journal of preventive cardiology (2023)
Long-term joint exposure to air pollutants including PM2.5, PM10, NO2, and NOx is substantially associated with increased risk of MI. Genetic susceptibility to MI strengthens such adverse joint association. Air pollutions together genetic and traditional factors enhances the accuracy of MI risk prediction.
Keyphrases
  • heavy metals
  • genome wide
  • particulate matter
  • air pollution
  • copy number
  • polycyclic aromatic hydrocarbons
  • left ventricular
  • risk assessment
  • reactive oxygen species
  • drug induced