COVID-19 and Mesenchymal Stem Cell Treatment; Mystery or Not.
Tunç AkkoçPublished in: Advances in experimental medicine and biology (2020)
On December 31, 2019, novel SARS-CoV2 spread from Wuhan China to more than 200 territories around world and the World Health Organization declared a COVID-19 pandemic on January 30, 2020. At this time there is no particular therapy, drug or vaccine available to deal with COVID-19. Today actual data indicates that about 17% of closed COVID-19 cases died. Health care professionals, ministry of health in countries and the public are trying to read the runes to see when the COVID-19 pandemic will be over. Although mild cases of COVID-19 can be controlled with antiviral, anti-inflammatory and immunomodulatory treatment, severe cases may need intensive care unit support and ventilation. Cytokine storms cause high inflammatory responses and pneumonia in severe cases. Mesenchymal stem cells are immunomodulatory and they have regenerative capacity. In this sense, mesenchymal stem cells may improve the patient's clinical and immunological response to COVID-19.
Keyphrases
- sars cov
- coronavirus disease
- mesenchymal stem cells
- healthcare
- respiratory syndrome coronavirus
- intensive care unit
- umbilical cord
- cell therapy
- stem cells
- mental health
- anti inflammatory
- emergency department
- public health
- early onset
- social media
- health information
- machine learning
- case report
- combination therapy
- extracorporeal membrane oxygenation
- drug induced
- electronic health record
- big data
- adverse drug
- artificial intelligence