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Deep phenotyping of socio-emotional skills in children with typical development, neurodevelopmental disorders, and mental health conditions: Evidence from the PEERS.

Vicki A AndersonSimone DarlingStephen HearpsDavid DarbyJulian DooleySkye McDonaldLyn S TurkstraAmy BrownMardee GreenhamLouise CrossleyGeorge CharalambousMiriam H Beauchamp
Published in: PloS one (2023)
Standardized parent questionnaires of child socio-emotional function reveal differences between children with typical and atypical development, but do not yield disorder-specific, socio-emotional profiles. In contrast, findings from the PEERS objective assessment suggest that that ASD, ADHD and ANX are associated with distinct socio-cognitive phenotypes, to more accurately guide and target management and treatment of impaired social competence.
Keyphrases
  • mental health
  • autism spectrum disorder
  • attention deficit hyperactivity disorder
  • young adults
  • healthcare
  • magnetic resonance
  • high throughput
  • working memory
  • magnetic resonance imaging
  • single cell
  • dna methylation