MRSA prevalence and hospital-level antibiotic use: A retrospective study across 122 acute-care hospitals.
Daniel J LivorsiRajeshwari NairBrian C LundBruce AlexanderBrice F BeckMichihiko GotoEli N PerencevichPublished in: Infection control and hospital epidemiology (2020)
We evaluated the relationship between local MRSA prevalence rates and antibiotic use across 122 VHA hospitals in 2016. Higher hospital-level MRSA prevalence was associated with significantly higher rates of antibiotic use, even after adjusting for case mix and stewardship strategies. Benchmarking anti-MRSA antibiotic use may need to adjust for MRSA prevalence.