Magnetization transfer ratio of the sciatic nerve differs between patients in type 1 and type 2 diabetes.

Christoph M MooshageLukas SchimpfleDimitrios TsilingirisZoltan KenderTaraneh Aziz-SafaieAnja HohmannJulia SzendroediPeter NawrothVolker SturmSabine HeilandMartin BendszusStefan KopfJohann M E JendeFelix T Kurz

Published in: European radiology experimental (2024)

• Magnetization transfer imaging detects distinct macromolecular nerve lesion patterns in diabetes patients. • Magnetization transfer ratio was lower in type 2 diabetes compared to type 1 diabetes. • Different pathophysiological mechanisms drive nerve damage in type 1 and 2 diabetes.

Keyphrases

type diabetes
glycemic control
end stage renal disease
cardiovascular disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
insulin resistance
skeletal muscle
patient reported outcomes
peripheral nerve