Genetic Diagnostics in Routine Osteological Assessment of Adult Low Bone Mass Disorders.

Ralf Oheim Elena Tsourdi Lothar SeefriedGisela BellerMax SchubachEik VettorazziJulian StürznickelTim RolvienNadja EhmkeAlena DelsmannFranca GenestUlrike KrügerTomasz ZemojtelFlorian BarvencikThorsten SchinkeFranz JakobLorenz C HofbauerStefan MundlosUwe Kornak

Published in: The Journal of clinical endocrinology and metabolism (2022)

The overlapping spectra of monogenic adult LBMD can be easily disentangled by genetic testing and the proposed clinical criteria can help to maximize the diagnostic yield.

Keyphrases

bone mineral density
genome wide
clinical practice
childhood cancer
gene expression
copy number
bone loss
postmenopausal women
molecular dynamics