Role of Hippo pathway dysregulation from gastrointestinal premalignant lesions to cancer.

Giulia SchiavoniBeatrice MessinaStefano ScaleraLorenzo MemeoCristina ColarossiMarzia MareGiovanni BlandinoGennaro CilibertoGiulia BonMarcello Maugeri-Saccà

Published in: Journal of translational medicine (2024)

The biology of premalignant Hippo signaling dysregulation needs further investigation in order to elucidate the evolutionary trajectories triggering cancer inititation and develop effective early therapeutic strategies targeting the Hippo/YAP pathway.

Keyphrases

papillary thyroid
squamous cell
depressive symptoms
lymph node metastasis
gene expression
genome wide
drug delivery