In vivo and in vitro palatability testing of a new paediatric formulation of valaciclovir.
Diane E T BastiaansLaura I ImmohrGertrude G ZeinstraRiet Strik-AlbersMiriam Pein-HackelbuschMichiel van der FlierAnton F J de HaanJaap Jan BoelensArjan C LankesterDavid Marinus BurgerAdilia WarrisPublished in: British journal of clinical pharmacology (2017)
The palatability of the new paediatric valaciclovir formulation was considered non-inferior to the reference formulation prepared out of crushed tablets. We were able to optimize the study design and number of children to be included in the palatability testing by using electronic tongue measurements.