Redox-Active Drug, MnTE-2-PyP5+, Prevents and Treats Cardiac Arrhythmias Preserving Heart Contractile Function.
Andrezza M BarbosaJosé F Sarmento-NetoJosé E R Menezes FilhoItamar C G JesusDiego S SouzaValério M N VasconcelosFagner D L GomesAline LaraJuliana S S AraújoSandra S MattosCarla Maria Lins de VasconcelosSilvia GuatimosimJader S CruzInes Batinic-HaberleDemetrius Antônio Machado AraujoJúlio Santos RebouçasEneas Ricardo de Morais GomesPublished in: Oxidative medicine and cellular longevity (2020)
MnTE-2-PyP5+ prevents and treats cardiac arrhythmias in rats. In contrast to most antiarrhythmic drugs, MnTE-2-PyP5+ preserves cardiac contractile function, arising, thus, as a prospective therapeutic for improvement of cardiac arrhythmia treatment.