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Potential pharmaceuticals targeting neuroimmune interactions in treating acute lung injury.

Di WuXiming LiaoJing GaoYixuan GaoQiang LiWei Gao
Published in: Clinical and translational medicine (2024)
The lungs present abundant nerve innervations. Neuroimmune interactions exert a modulatory effect in the onset and progression of lung inflammatory diseases, especially acute lung injury. The advancements of potential drugs for ALI targeting neuroimmune crosstalk at different stages from preclinical investigation to clinical trials are elaborated. Point out the direction for the development of neuroimmune pharmacology in the future.
Keyphrases
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  • oxidative stress
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  • stem cells
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  • climate change
  • open label
  • study protocol
  • drug induced