Chemoradiotherapy with high-dose cisplatin compared with weekly cisplatin for locally advanced head and neck squamous cell carcinoma.

Ryan T Hughes Mercedes PorosnicuBeverly J LevineThomas W Lycan Rachel F ShenkerBart A FrizzellKathryn M Greven

Published in: Journal of medical imaging and radiation oncology (2021)

Concurrent HDC is associated with increased total cisplatin intensity, OS and DFS compared with weekly cisplatin regimens. LRC was not associated with chemotherapy regimen. HDC remains the standard of care; WC40 is a reasonable alternative that does not appear to sacrifice LRC.

Keyphrases

high dose
locally advanced
healthcare
palliative care
rectal cancer
low dose
squamous cell carcinoma
radiation therapy
high intensity
stem cell transplantation
pain management