Genomic alterations in neuroendocrine prostate cancer: A systematic review and meta-analysis.

Junru ChenMingchen ShiStephen Yiu Chuen ChoiYu WangDong LinHao Zeng Yuzhuo Z Wang

Published in: BJUI compass (2023)

This study presents the comprehensive prevalence of common genomic alterations and potentially actionable targets in NEPC and reveals the genomic differences between de novo NEPC and t-NEPC. Our findings highlight the importance of genomic testing in patients for precision medicine and provide insights into future studies exploring different NEPC subtypes.

Keyphrases

prostate cancer
copy number
end stage renal disease
ejection fraction
newly diagnosed
radical prostatectomy
prognostic factors
peritoneal dialysis