Glutamatergic PPT neurons control wakefulness and locomotion via distinct axonal projections.
Daniel KroegerJack ThundercliffeAlex PhungRoberto De LucaCarolyn GeraciSamuel BraggKayleen J McCaffertySathyajit S BandaruElda ArrigoniThomas E ScammellPublished in: Sleep (2022)
These findings demonstrate the importance of the PPT vGluT2 neurons in driving various aspects of arousal and show that heterogeneous brain nuclei, such as the PPT, can promote a variety of behaviors via distinct axonal projections.