Imaging diagnosis and legal implications of brain injury in survivors following single intrauterine fetal demise from monochorionic twins - a review of the literature.
Gheorghe CruciatGeorgiana Irina NemetiRoxana Popa-StanilaAndreea FlorianIulian Gabriel GoidescuPublished in: Journal of perinatal medicine (2021)
Brain injury of the surviving twin from monochorionic pregnancies following intrauterine fetal demise during the second and third trimesters is a rare but severe complication. Monochorionicity and gestational age at the time of stillbirth seem to be decisive factors in terms of long-term neurologic outcome prediction for the survivor. Magnetic resonance imaging (MRI), diffusion weighted imaging (DWI) in particular, seem to bring the earliest and most accurate diagnosis. Ultrasound detection of brain damage is possible in later stages of fetal brain injury. It is essential to provide early diagnosis and multidisciplinary counsel to the parents to ensure informed decision making. For couples who choose to terminate pregnancy legislation related to late abortion might lead to further distress. Our paper aims to stress the importance of MRI DWI in the evaluation of surviving twins following single intrauterine fetal demise in monochorionic pregnancies and the delicate context of the medical professionals and parents facing this clinical situation, sometimes complicated by legal constraints.
Keyphrases
- brain injury
- diffusion weighted imaging
- gestational age
- magnetic resonance imaging
- preterm birth
- contrast enhanced
- subarachnoid hemorrhage
- birth weight
- cerebral ischemia
- diffusion weighted
- decision making
- computed tomography
- high resolution
- healthcare
- oxidative stress
- white matter
- weight gain
- mass spectrometry
- pregnant women
- multiple sclerosis
- drug induced
- blood brain barrier
- label free