Fingolimod promotes blood-nerve barrier properties in vitro.

Hideaki NishiharaToshihiko MaedaYasuteru SanoMaho UenoNana OkamotoYukio TakeshitaFumitaka ShimizuMichiaki KogaTakashi Kanda

Published in: Brain and behavior (2018)

Fingolimod-phosphate directly modifies the BNB and enhances barrier properties. This mechanism may be a viable therapeutic target for CIDP, and fingolimod may be useful in patients with typical CIDP who have severe barrier disruption.

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multiple sclerosis