Epileptic spasms are associated with increased stereo-electroencephalography derived functional connectivity in tuberous sclerosis complex.
Andrew NealRomain BouetStanislas LagardeKarine Ostrowsky-CosteLouis MaillardPhilippe KahaneRenaud TouraineHelene CatenoixAlexandra MontavontJean IsnardAlexis A ArzimanoglouMarc HermierMarc GuenotFabrice BartolomeiSylvain RheimsJulien JungPublished in: Epilepsia (2022)
Increased cortical synchrony among both tuber and nontuber networks is characteristic of patients with ES and independent of both EZ organization and tuber epileptogenicity. This further supports the prospect of FC biomarkers aiding treatment paradigms in TSC.