Effect of Magnesium Acetyltaurate and Taurine on Endothelin1-Induced Retinal Nitrosative Stress in Rats.

Natasha Najwa Nor ArfuzirRenu Agarwal Igor IezhitsaPuneet AgarwalSabrilhakim SidekAlexander SpasovAlexander OzerovNafeeza Mohd Ismail

Published in: Current eye research (2018)

MgAT and TAU prevent ET1-induced retinal cell apoptosis by reducing retinal nitrosative stress in Sprague Dawley rats. Addition of TAU to Mg seems to enhance the efficacy of TAU compared to when given alone. Moreover, the pretreatment with MgAT/TAU showed higher efficacy compared to co- or posttreatment.

Keyphrases

optical coherence tomography
cerebrospinal fluid
diabetic retinopathy
high glucose
diabetic rats
optic nerve
cell proliferation
drug induced
endothelial cells