Sodium-glucose cotransporter-2 inhibitors and the risk of gout in patients with type 2 diabetes mellitus: A propensity-score-matched, new-user design study with an active comparator using the IQVIA Medical Research Data UK database.

Anuradhaa SubramanianKrishna GokhaleChristopher A R SainsburyKrishnarajah NirantharakumarKonstantinos A Toulis

Published in: Diabetes, obesity & metabolism (2022)

In this nationwide study, no difference in the incidence of gout was documented in patients treated with SGLT2 inhibitors compared to DPP-4 inhibitor users. This neutral finding remained consistent in sensitivity analyses.

Keyphrases

uric acid
healthcare
risk factors
electronic health record
emergency department
big data
metabolic syndrome
machine learning